Africa continues to suffer from European imperialism and its related extensive ills like exploitation, ethnocide, corruption, dictatorship, embezzlement, and murder. In his plays, the Cameroonian dramatist, Bole Butake, handles numerous problems plaguing Cameroon and other African countries, and one of these is bad leadership caused by neocolonialism. This study examined Butake’s perspectives on the connection between European expansionism and African autochthonous spirituality. Using Cultural Resistance by David Jeffress as the theoretical framework, the work sought to answer the question: What is Bole Butake’s vision of the link between neocolonialism and African sacredness? The paper, which is divided into three parts, concludes that Butake projects African traditional religion as a solution to neocolonialism and its negative offshoots. It opines that African spiritual entities should be associated with governance as elements of regulation, control, and punishment so that bad leadership and the subsequent suffering of Africans can be mitigated or eliminated.